How do you find the [urate] that will cause sodium urate solid to form?Gout is caused by an error in nucleic acid metabolism that leads to a buildup of uric acid in body fluids, which is deposited as slightly soluble sodium urate (C5H3N4O3Na) in the soft tissues of joints. If the extracellular [Na+] is 0.26 M and the solubility in water of sodium urate is 0.067 g/100 mL, what is the minimum urate ion concentration (abbreviated [Ur - ]) that will cause a deposit of sodium urate?
skipper
Molar mass of sodium urate = 190.09
0.067 g / 190.09 = 0.00035 mol
0.00035 mol / 0.100 L = 0.0035 M
let NaU = sodium urate
Ksp = [Na++][U-] = 0.0035 x 0.0035 = 1.24x10^-5
1.24x10^-5 = (0.26)x(U-)
[U-] = 4.8x10^-5 M
4.8x10^-5 M x 190.09 = 0.0091 g/liter = 0.00091 g/100 mL
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How do you find the [urate] that will cause sodium urate solid to form?
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